Methyl salicylate should not be used with anticoagulants e.g. warfarin as it may potentiate the side effects of warfarin. Methyl Salicylate, camphor and capsaicin combination shall not be used with anti-anginal drugs e.g. captopril, ramipril, amlodipine, etc. Capsaicin may increase stomach acid and reduce the effect of stomach acid reducers like cimetidine, omeprazole, etc. Capsaicin may also decrease the pain relieving effect of aspirin and increase the risk of bleeding associated with aspirin.